diff --git a/packages/nodes-base/nodes/Code/Pyodide.ts b/packages/nodes-base/nodes/Code/Pyodide.ts
index 23bcabbde8..42b70ea231 100644
--- a/packages/nodes-base/nodes/Code/Pyodide.ts
+++ b/packages/nodes-base/nodes/Code/Pyodide.ts
@@ -1,3 +1,4 @@
+import { dirname } from 'node:path';
 import type { PyodideInterface } from 'pyodide';
 
 let pyodideInstance: PyodideInterface | undefined;
@@ -5,7 +6,8 @@ let pyodideInstance: PyodideInterface | undefined;
 export async function LoadPyodide(packageCacheDir: string): Promise<PyodideInterface> {
 	if (pyodideInstance === undefined) {
 		const { loadPyodide } = await import('pyodide');
-		pyodideInstance = await loadPyodide({ packageCacheDir });
+		const indexURL = dirname(require.resolve('pyodide'));
+		pyodideInstance = await loadPyodide({ indexURL, packageCacheDir });
 
 		await pyodideInstance.runPythonAsync(`
 from _pyodide_core import jsproxy_typedict